Dr. Rajagopalan Bhaskaran,  Biophysics

Dr. Xianyang Liang,  Chemistry

Dr. Steven R. Van Doren, Biophysics

Dr. Mark O. Palmier, Biochemistry

Recent publications

Bhaskaran, R., Palmier, M. O., Bagegni, N. A., Liang, X., and Van Doren, S. R. Solution structure of inhibitor-free human metalloelastase (MMP-12) indicates an internal conformational adjustment (2007) J Mol Biol 374, 1333-1344.

Palmier, M. O., and Van Doren, S. R. Rapid determination of enzyme kinetics from fluorescence: Overcoming the inner filter effect (2007) Anal Biochem 371, 43-51.

Bhaskaran, R., Palmier, M. O., Lauer-Fields, J. L., Fields, G. B., and Van Doren, S. R. MMP-12 catalytic domain recognizes triple-helical peptide models of collagen V with exosites and high activity (2008) J Biol Chem 283, 21779-21788.

Van Doren, S. R., Shuo Wei, Guanghua Gao, DaGue, B. B., Palmier, M. O., Bahudhanapati, H., and Brew, K.  Inactivation of N-TIMP-1 by N-terminal Acetylation when Expressed in Bacteria (2008) Biopolymers (online).

Telugu, B. P. V. L., Palmier, M. O., Van Doren, S. R., Green J. A.  Bovine Pregnancy-Associated Glycoprotein 2 and 12 are both peptidases that possess distinct proteolytic activity and specificity (2008)  Biochem J.  (submitted)

Liang, X. and Van Doren, S. R., Mechanistic Insights into Phosphoprotein-Binding FHA Domains (2008) Acc. Chem. Res. (online)

Contact Information  

Osage Biotech, LLC
169 Etlah Hills Ct.
Berger, MO 63014

Email  -  markopalmier@osagebiotech.com
Phone -  (314) 210-0621                                                

www.osagebiotech.com